Skyrim Alchemy Profitability Calculator
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The effect Weakness to Frost (45) can be achieved in a potion if you mix these ingredients:

Abecean Longfin
Elves Ear
Fire Salts
Ice Wraith Teeth
White Cap

Here is a list of possible combinations of ingredients:

White Cap
Ice Wraith Teeth
=>Weakness to Frost
Fortify Heavy Armor
=>105
  + Vampire Dust+ Restore Magicka, Invisibility+ 386 = 491
  + Nirnroot+ Invisibility+ 357 = 462
  + Luna Moth Wing+ Invisibility+ 357 = 462
  + Crimson Nirnroot+ Invisibility+ 357 = 462
  + Chaurus Eggs+ Invisibility+ 357 = 462
  + Moon Sugar+ Restore Magicka, Weakness to Fire+ 83 = 188
  + Frost Salts+ Restore Magicka, Weakness to Fire+ 83 = 188
  + Powdered Mammoth Tusk+ Weakness to Fire+ 54 = 159
  + Juniper Berries+ Weakness to Fire+ 54 = 159
  + Bleeding Crown+ Weakness to Fire+ 54 = 159
  + Red Mountain Flower+ Restore Magicka, Ravage Magicka+ 45 = 150
  + Grass Pod+ Restore Magicka, Ravage Magicka+ 45 = 150
  + Taproot+ Restore Magicka+ 29 = 134
  + Pearl+ Restore Magicka+ 29 = 134
  + Mora Tapinella+ Restore Magicka+ 29 = 134
  + Human Flesh+ Restore Magicka+ 29 = 134
  + Giant Lichen+ Restore Magicka+ 29 = 134
  + Fire Salts+ Restore Magicka+ 29 = 134
  + Elves Ear+ Restore Magicka+ 29 = 134
  + Ectoplasm+ Restore Magicka+ 29 = 134
  + Dwarven Oil+ Restore Magicka+ 29 = 134
  + Creep Cluster+ Restore Magicka+ 29 = 134
  + Briar Heart+ Restore Magicka+ 29 = 134
  + Orange Dartwing+ Ravage Magicka+ 16 = 121
  + Lavender+ Ravage Magicka+ 16 = 121
  + Frost Mirriam+ Ravage Magicka+ 16 = 121
 
White Cap
Fire Salts
=>Weakness to Frost
Restore Magicka
=>74
  + Taproot+ Regenerate Magicka+ 203 = 277
  + Salt Pile+ Regenerate Magicka+ 203 = 277
  + Moon Sugar+ Regenerate Magicka+ 203 = 277
  + Jazbay Grapes+ Regenerate Magicka+ 203 = 277
  + Garlic+ Regenerate Magicka+ 203 = 277
  + Dwarven Oil+ Regenerate Magicka+ 203 = 277
  + Snowberries+ Resist Fire+ 96 = 170
  + Mudcrab Chitin+ Resist Fire+ 96 = 170
  + Fly Amanita+ Resist Fire+ 96 = 170
  + Elves Ear+ Resist Fire+ 96 = 170
  + Dragons Tongue+ Resist Fire+ 96 = 170
  + Bone Meal+ Resist Fire+ 96 = 170
  + Thistle Branch+ Fortify Heavy Armor+ 60 = 134
  + Slaughterfish Scales+ Fortify Heavy Armor+ 60 = 134
  + Sabre Cat Tooth+ Fortify Heavy Armor+ 60 = 134
  + Ice Wraith Teeth+ Fortify Heavy Armor+ 60 = 134
  + Red Mountain Flower+ Ravage Magicka+ 16 = 90
  + Orange Dartwing+ Ravage Magicka+ 16 = 90
  + Lavender+ Ravage Magicka+ 16 = 90
  + Grass Pod+ Ravage Magicka+ 16 = 90
  + Frost Mirriam+ Ravage Magicka+ 16 = 90
 
White Cap
Elves Ear
=>Weakness to Frost
Restore Magicka
=>74
  + Spider Egg+ Fortify Marksman+ 134 = 208
  + Juniper Berries+ Fortify Marksman+ 134 = 208
  + Canis Root+ Fortify Marksman+ 134 = 208
  + Snowberries+ Resist Fire+ 96 = 170
  + Mudcrab Chitin+ Resist Fire+ 96 = 170
  + Fly Amanita+ Resist Fire+ 96 = 170
  + Fire Salts+ Resist Fire+ 96 = 170
  + Dragons Tongue+ Resist Fire+ 96 = 170
  + Bone Meal+ Resist Fire+ 96 = 170
  + Thistle Branch+ Fortify Heavy Armor+ 60 = 134
  + Slaughterfish Scales+ Fortify Heavy Armor+ 60 = 134
  + Sabre Cat Tooth+ Fortify Heavy Armor+ 60 = 134
  + Ice Wraith Teeth+ Fortify Heavy Armor+ 60 = 134
  + Red Mountain Flower+ Ravage Magicka+ 16 = 90
  + Orange Dartwing+ Ravage Magicka+ 16 = 90
  + Lavender+ Ravage Magicka+ 16 = 90
  + Grass Pod+ Ravage Magicka+ 16 = 90
  + Frost Mirriam+ Ravage Magicka+ 16 = 90
 
White Cap
Abecean Longfin
=>Weakness to Frost=>45
  + Small Antlers+ Weakness to Poison, Fortify Restoration+ 190 = 235
  + Human Flesh+ Restore Magicka, Fortify Sneak+ 163 = 208
  + Frost Mirriam+ Ravage Magicka, Fortify Sneak+ 150 = 195
  + Small Pearl+ Fortify Restoration+ 134 = 179
  + Salt Pile+ Fortify Restoration+ 134 = 179
  + Purple Mountain Flower+ Fortify Sneak+ 134 = 179
  + Powdered Mammoth Tusk+ Fortify Sneak+ 134 = 179
  + Hawk Feathers+ Fortify Sneak+ 134 = 179
  + Cyrodilic Spadetail+ Fortify Restoration+ 134 = 179
  + Beehive Husk+ Fortify Sneak+ 134 = 179
  + Sabre Cat Tooth+ Fortify Heavy Armor, Weakness to Poison+ 116 = 161
  + Giant Lichen+ Restore Magicka, Weakness to Poison+ 85 = 130
  + Thistle Branch+ Fortify Heavy Armor+ 60 = 105
  + Slaughterfish Scales+ Fortify Heavy Armor+ 60 = 105
  + Ice Wraith Teeth+ Fortify Heavy Armor+ 60 = 105
  + Pine Thrush Egg+ Weakness to Poison+ 56 = 101
  + Deathbell+ Weakness to Poison+ 56 = 101
  + Chaurus Eggs+ Weakness to Poison+ 56 = 101
  + Bleeding Crown+ Weakness to Poison+ 56 = 101
  + Red Mountain Flower+ Restore Magicka, Ravage Magicka+ 45 = 90
  + Grass Pod+ Restore Magicka, Ravage Magicka+ 45 = 90
  + Vampire Dust+ Restore Magicka+ 29 = 74
  + Taproot+ Restore Magicka+ 29 = 74
  + Pearl+ Restore Magicka+ 29 = 74
  + Mora Tapinella+ Restore Magicka+ 29 = 74
  + Moon Sugar+ Restore Magicka+ 29 = 74
  + Frost Salts+ Restore Magicka+ 29 = 74
  + Fire Salts+ Restore Magicka+ 29 = 74
  + Elves Ear+ Restore Magicka+ 29 = 74
  + Ectoplasm+ Restore Magicka+ 29 = 74
  + Dwarven Oil+ Restore Magicka+ 29 = 74
  + Creep Cluster+ Restore Magicka+ 29 = 74
  + Briar Heart+ Restore Magicka+ 29 = 74
  + Orange Dartwing+ Ravage Magicka+ 16 = 61
  + Lavender+ Ravage Magicka+ 16 = 61